Phacilitate Talks

Phacilitate Talks LIVE @ ATC: Investment & Funding with Amritha Jaishankar

In this bonus episode of Phacilitate Talks, recorded LIVE at Advanced Therapies Connect (September 2021), Georgi Makin speaks to Amritha Jaishankar, Executive Director at Maryland Stem Cell Research Fund. 

This investment and funding Spotlight episode focuses on the past year of high investment, Women in Advanced Therapies and what to expect from Amritha at Advanced Therapies Connect later today. 

It's not too late to join us! Register and join the conversation via: https://bit.ly/3CSHZKX 

QUICK LINKS: 

• Georgi Makin: https://bit.ly/3iefkYZ
• Amritha Jaishankar: https://bit.ly/3zMkG3z 

Phacilitate Talks LIVE @ ATC: European Spotlight with Miguel Forte and Magali Taiel

In this bonus episode of Phacilitate Talks, recorded LIVE at Advanced Therapies Connect (September 2021), Georgi Makin speaks to Miguel Forte, CEO at Bone Therapeutics and Magali Taiel, CMO at GenSight Biologics. 

This European Spotlight episode focuses on unique challenges in the industry in Europe, as well as what each speaker will be discussing at the event. 

It's not too late to join us! Register and join the conversation via: https://bit.ly/3zLP3qH

QUICK LINKS: 

• Georgi Makin: https://bit.ly/3iefkYZ
• Miguel Forte: https://bit.ly/2Ya7U1P
• Magali Taiel: https://bit.ly/3ofQGei

Private Equity vs Strategics with Phil Vanek and Joe LaPlume

The third episode of season 2 of Phacilitate Talks allows us to finally visit a financial theme as we pitch private equity against strategics… 

Watch the full episode via the Phacilitate website: https://bit.ly/3nTtxy1  

Welcome to the third episode of season 2 of Phacilitate Talks! This week, we are finally able to re-visit our schedule as we discuss the financial landscape advanced therapies, pitching private equity against strategics.  

As we continue our journey on the road to Miami, Phacilitate Editor, Georgi Makin, and CEO of Dark Horse Consulting, Anthony Davies, invite guests to discuss key issues in the cell and gene therapy industry, asking the big questions that everyone wants the answer to.   

Find out more about Advanced Therapies Week 2022: https://bit.ly/3my6QyG  

IN THE BLUE CORNER… 

In this episode, Anthony and Georgi are joined by Phil Vanek, CTO at Gamma Biosciences, and Joe LaPlume, Corporate Executive Vice President at Charles River Laboratories.  

The group discusses how the different companies operate, the importance of financial modelling, key headlines from a year of high investment, and how the two different companies or strategies might be able to work together before ‘going shopping’ for the perfect next opportunity for investment.  

QUICK LINKS 

• Phil Vanek: https://bit.ly/2W5g1fe  
• Joe LaPlume: https://bit.ly/3ksD8d0 
• Anthony Davies: https://bit.ly/3B7EQpJ    
• Christina Fuentes: https://bit.ly/2YSihaL   
• Georgi Makin: https://bit.ly/3jbg5Tj  

The opinions expressed in this podcast are solely those of the interviewees’ and do not necessarily reflect the views or opinions of their respective employers. 

This podcast has been produced in partnership with Dark Horse Consulting: https://darkhorseconsultinggroup.com/    

Does AAV Have a Long Term Future? With Nicole Paulk

For the second episode of season 2 of Phacilitate Talks, we interrupt planned transmission to discuss the future of AAV with Nicole Paulk, following the recent FDA AdComm.

Welcome to the second episode of season 2 of Phacilitate Talks! This week, we interrupt planned transmission to discuss the future of AAV following the FDA AdComm in early September.

Watch the full episode via the Phacilitate website: https://bit.ly/3hrQVP3

As we continue our journey on the road to Miami, Phacilitate Editor, Georgi Makin, and CEO of Dark Horse Consulting, Anthony Davies, invite guests to discuss key issues in the cell and gene therapy industry, asking the big questions that everyone wants the answer to. 

Find out more about Advanced Therapies Week 2022: https://bit.ly/3my6QyG 

In this second episode, Anthony and Georgi are joined by Nicole Paulk, AAV Gene Therapy Professor at UCSF, as they discuss reactions to the AdComm meeting, and what we should expect from AAV in the future.

The group discusses a perhaps unfair perception of AAV, novel technologies poised to advance the field, empty capsids, and what guidance is needed to help progress AAV.

QUICK LINKS

• Nicole Paulk: https://bit.ly/3k65vxA 
• Anthony Davies: https://bit.ly/3B7EQpJ 
• Christina Fuentes: https://bit.ly/2YSihaL 
• Georgi Makin: https://bit.ly/3jbg5Tj 

The opinions expressed in this podcast are solely those of the interviewees’ and do not necessarily reflect the views or opinions of their respective employers.

This podcast has been produced in partnership with Dark Horse Consulting: https://darkhorseconsultinggroup.com/  

The Future of Cell and Gene Therapy with Bruce Levine and Audrey Greenberg

Season 2 of Phacilitate Talks kicks off with a bang as Bruce Levine and Audrey Greenberg explore key questions associated with building capacity, acquiring talent and looking ahead in a post-pandemic world.  

Welcome to season 2 of Phacilitate Talks! This season, we have left the pandemic norm and returned to offices, in-person meetings and even live events!  

Watch the full video via the Phacilitate website: https://bit.ly/3kn7Naf  

As we begin our journey on the road to Miami, Phacilitate Editor, Georgi Makin, and CEO of Dark Horse Consulting, Anthony Davies, invite guests to discuss key issues in the cell and gene therapy industry, asking the big questions that everyone wants the answer to.  

Find out more about Advanced Therapies Week 2022: https://bit.ly/3my6QyG 

In this first episode, Anthony and Georgi are joined by Bruce Levine, Barbara and Edward Netter Professor in Cancer Gene Therapy at the University of Pennsylvania, and Audrey Greenberg, Co-Founder, Discovery Labs & Centre for Breakthrough Medicines, as they discuss the future of cell and gene therapy.  

The group discusses different models for CDMO capacity expansion, acquiring appropriate talent to manage expansion opportunities and the resulting ripple effect and rapid development in the field following multiple, recent high-profile mergers and acquisitions.   

 

*Bonus footage – “Are you talking to the FDA yet?” 

As a special treat for launching the new season, we have shared an extra segment exclusive to watch on the Phacilitate website.  

In this bonus clip, Anthony, Audrey and Bruce discuss the process (and best practice) for engaging the FDA in the product development pipeline for cell and gene therapies, sharing top tips and exclusive insights from their combined experience in cell and gene therapy development.  

The group discusses the idea that “perfect is the enemy of good” – a quote attributed to Peter Marks (CBER, FDA) from a recent ISCT meeting – outlining key issues associated with attitudes and approaches associated with the idea of perfection with cell and gene therapies, as well as the requirements for regulating them.  

Watch the bonus footage here: https://bit.ly/3krMrbI  

QUICK LINKS 

• Bruce Levine: https://bit.ly/3DdC5oC  
• Audrey Greenberg: https://bit.ly/3DhDxpR  
• Anthony Davies: https://bit.ly/3B7EQpJ  
• Christina Fuentes: https://bit.ly/2YSihaL 
• Georgi Makin: https://bit.ly/2Wg7Qgl  

The opinions expressed in this podcast are solely those of the interviewees’ and do not necessarily reflect the views or opinions of their respective employers. 

This podcast has been produced in partnership with Dark Horse Consulting: https://darkhorseconsultinggroup.com/  

The impact of covid-19 and future pandemics on getting advanced therapies to patients

Welcome to the first episode of Phacilitate Talks!

Lindsey Clarke the European Head of Cell and Gene Therapy at bio-techne, Anthony Davies, CEO of Dark Horse Consulting and Cenk Sumen CTO of Stemson Therapeutics dig into how their teams have adjusted to remote work, how covid-19 has impacted clinical trials and what we do as global community to better prepare for the next pandemic.

 

In this episode I refer to a webinar with Kings College, Sexton Biotechnologies and BioBridge Global which you can sign up for here - https://bit.ly/2WkhOJs

 

If you’re not already, don’t forget to sign-up as a Phacilitate member, it’s FREE! Every fortnight you’ll get the latest market intelligence, new ideas and exclusive events offers straight to your inbox. Join a community with the same goal; to help advance a new standard in healthcare.

www.phacilitate.co.uk/subscribe

Phacilitate Talks #9 Nina Bauer, MilliporeSigma and Lance Holland, bluebird bio - PART 2

Part 2 of Anthony and Michael's meet up to Nina Bauer and Lance Holland.

*Opinions expressed are solely the interviewee's own and do not express the views or opinions of their respective employers.*

 

The bulk of the chat was around Mesoblast's pending FDA decision for Ryoncil, their pediatric graft versus host disease therapy. The panel took it to a vote on will it be approved or rejected. Listen and find out how the panel judged it and of course, you can see the widely reported outcome in various news outlets.

 

Register for FREE for Phacilitate's next member event! Advanced Therapies Connect will take place on the 26-27 January 2021 and will be 100% virtual!

https://www.advancedtherapiesconnect.com/

 

Lance's link to Mass Bio Ed

https://www.massbioed.org

 

Dark Horse Consulting are recruiting!

https://darkhorseconsultinggroup.com/careers/

 

And so is Nina's team at MilliporeSigma!

https://www.merckgroup.com/en/careers.html

 

Finally, if you’re not already, don’t forget to sign-up as a Phacilitate member, it’s FREE! Every fortnight you’ll get the latest market intelligence, new ideas and exclusive event offers straight to your inbox.

 

Join a community with the same goal; to help advance a new standard in healthcare.

https://www.phacilitate.co.uk/membership

 

Emily and Tom Whitehead, Women in Advanced Therapies Special

The fourth in our series of Women in Advanced Therapies interviews, where we'll be talking to a selection of the women featured in the '11 Most Influential Women in Advanced Therapies' eBook.

 

Link to the eBook - https://bit.ly/2HOGR3Q

 

In this episode we're delighted to be interviewing Emily Whitehead, cancer survivor and ambassador for CAR-T therapy. At only six-years-old, Emily Whitehead was facing a life-threatening recurrence of acute lymphoblastic leukemia, the most common childhood cancer.

 

Emily's cancer resisted over 16 months of chemotherapy treatments when her parents were told that her cancer had relapsed and that she would not survive. Jana Stoudemire exclusively interviews Emily alongside her father Tom.

 

Praying for Emily: The Faith, Science, and Miracles That Saved Our Daughter is available now on hardback - https://www.amazon.co.uk/Praying-Emily

 

If you’re not already, don’t forget to sign-up as a Phacilitate member, it’s FREE! Every fortnight you’ll get the latest market intelligence, new ideas and exclusive events offers straight to your inbox.

Join a community with the same goal; to help advance a new standard in healthcare.

www.phacilitate.co.uk/subscribe 

Nina Bauer, MilliporeSigma and Lance Holland, bluebird bio - PART I

In this episode, Anthony and Michael talk to Nina Bauer, the Head of Commercial, Gene Editing and Novel Modalities at MilliporeSigma and Lance Holland, Associate Director, External Vector Manufacturing at bluebird bio.

 

The discussion starts with a look at the challenges brought by Covid-19 with regards to finding a new way of working with your CDMO, in particular conducting audits. Anthony's solution? Use GoPros!

 

Nina puts a question to the group around recruiting diverse talent. With a major talent gap across our industry, this surely has to have many benefits?

 

The conversation flowed so well that we ran out of time, keep your eye out for part II of this conversation coming soon...

 

If you’re not already, don’t forget to sign-up as a Phacilitate member, it’s FREE! Every fortnight you’ll get the latest market intelligence, new ideas and exclusive event offers straight to your inbox.

Join a community with the same goal; to help advance a new standard in healthcare.

https://www.phacilitate.co.uk/membership

Episode 6 Dave Smith and Oliver Ball

In this episode, Anthony and I have a great chat with David Smith, President and Chief Commercial Officer of Akron Biotech and Oliver Ball, Business Development Manager at Stemmatters.

Oliver graduated with distinction from Kings College London in 2016 with a Masters in 'Cellular Therapy From Bench to Market'.

David Smith has over 20 years of experience in cell therapy and has been involved in commercialising several therapeutic products all over the globe.

It's a great conversation with two people at different stages of their cell and gene therapy career but with the same passion for seeing innovative tools come to market.

 

Here's the link to the non-dilutive funding report in partnership with Freemind Group!

Enjoy and, as always, please share your feedback.